Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Polygenic Risk Score for Schizophrenia and Treatment-Resistant Schizophrenia.

Schizophrenia bulletin - 1 Sept 2017

Wimberley Theresa, Gasse Christiane, Meier Sandra Melanie, Agerbo Esben, MacCabe James H, Horsdal Henriette Thisted

Abstract excerpt

Treatment-resistant schizophrenia (TRS) affects around one-third of individuals with schizophrenia. Although a number of sociodemographic and clinical predictors of TRS have been identified, data on the genetic risk of TRS are sparse. We aimed to investigate the association between a polygenic risk score for schizophrenia and treatment resistance in patients with schizophrenia. We conducted a nationwide,...

Topics

Join the communities discussing this publication.

Antipsychotic Agents
Denmark
Drug Resistance
Follow-Up Studies
Multifactorial Inheritance

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Open in PubMed Open full text

Identifiers

PMID: 28184875
DOI: 10.1093/schbul/sbx007
PMCID: PMC5581885

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polygenic Risk Score for Schizophrenia and Treatment-Resistant Schizophrenia.PMID 28184875Read ↗

Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia.Semantic proximity Read ↗

Genome-wide association analysis of treatment resistant schizophrenia for variant discovery and polygenic assessment.Semantic proximity Read ↗

Genome-wide association analysis of treatment resistant schizophrenia for variant discovery and polygenic assessmentSemantic proximity Read ↗

Deconstructing the genetic architecture of treatment-resistant schizophrenia in East Asian ancestry.Semantic proximity Read ↗

Indicated association between polygenic risk score and treatment-resistance in a naturalistic sample of patients with schizophrenia spectrum disordersSemantic proximity Read ↗

Genomic stratification of clozapine prescription patterns using schizophrenia polygenic scoresSemantic proximity Read ↗

Systems-Level Analysis of Genetic Variants Reveals Functional and Spatiotemporal Context in Treatment-resistant Schizophrenia.Semantic proximity Read ↗

Associations Between Polygenic Risk Score Loading, Psychosis Liability, and Clozapine Use Among Individuals With SchizophreniaSemantic proximity Read ↗

Higher polygenic risk scores for schizophrenia may be suggestive of treatment non-response in major depressive disorder.Semantic proximity Read ↗

Polygenic risk score analyses of symptoms and treatment response in an antipsychotic-naive first episode of psychosis cohort.Semantic proximity Read ↗

Higher polygenic risk scores for schizophrenia may be suggestive of treatment non-response in major depressive disorderSemantic proximity Read ↗

Transdiagnostic Effects of Schizophrenia Polygenic Scores on Treatment Outcomes in Major Psychiatric DisordersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.