Article
Early-life tobacco exposure is causally implicated in aberrant RAG-mediated recombination in childhood acute lymphoblastic leukemia
2024-06-20
Abstract excerpt
<title>Abstract</title> <p>Acute lymphoblastic leukemia (ALL) is the most common cancer in children, yet few environmental risk factors have been identified. We previously found an association between early-life tobacco smoke exposure and frequency of somatic deletions of 8 leukemia driver genes among childhood ALL patients in the California Childhood Leukemia Study. To expand analysis genome-wide and examine pot...
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Identifiers and source
- Literature Corpus work
- ea5954e7-178d-591e-b4f0-04ddf5b84715
- DOI
- 10.21203/rs.3.rs-4510345/v1
