Article
Tumor-Immune Partitioning and Clustering (TIPC) algorithm reveals distinct signatures of tumor-immune cell interactions within the tumor microenvironment
2020-05-30
Abstract excerpt
Growing evidence supports the importance of understanding tumor-immune spatial relationship in the tumor microenvironment in order to achieve precision cancer therapy. However, existing methods, based on oversimplistic cell-to-cell proximity, are largely confounded by immune cell density and are ineffective in capturing tumor-immune spatial patterns. Here we developed a novel computational algorithm, termed Tumor-...
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Identifiers and source
- Literature Corpus work
- ea3ed29b-6879-5de3-9255-18ace419e3e6
- DOI
- 10.1101/2020.05.29.111542