Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Immune cell landscape reveals 5 immune-related subtypes and molecular characteristics with prognostic and therapeutic implications in pan-cancer.

Journal of leukocyte biology - 8 Jun 2026

Wang Hongjiu, Wang Na, He Siyu, Wen Xiaoling, Xiong Feifan, Guo Denghui, Shen Jie, Li Sirui, Liang Jiangying, Huang Xinyao, Yi Ziyang, Zhai Pengyuan, Gao Xiao Ling, Wang Zhenzhen, Li Xia

Abstract excerpt

The immunotherapy represents the most promising new cancer treatment approach but due to the high heterogeneity of the tumor microenvironment among patients, only a small portion of patients respond to a certain immunotherapy. Therefore, identifying the immune-related subtypes and immune molecular characteristics is of great guiding significance for improving the response and results of immunotherapy and...

Topics

Humans
Neoplasms
Prognosis
Tumor Microenvironment
Biomarkers, Tumor
Mutation
Immunotherapy
Isocitrate Dehydrogenase
Clustering Algorithms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 42367149
DOI: 10.1093/jleuko/qiag062

Genes

IDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immune cell landscape reveals 5 immune-related subtypes and molecular characteristics with prognostic and therapeutic implications in pan-cancer.PMID 42367149Read ↗

A Single-Cell Tumor Immune Atlas for Precision OncologySemantic proximity Read ↗

A novel immune subtype classification of ER-positive, PR-negative and HER2-negative breast cancer based on the genomic and transcriptomic landscapeSemantic proximity Read ↗

Immunogenomic landscape of hematological malignanciesSemantic proximity Read ↗

A Pan-cancer Landscape of Interactions between Solid Tumors and Infiltrating Immune Cell PopulationsSemantic proximity Read ↗

Unraveling the Expression Patterns of Immune Checkpoints Identifies New Subtypes and Emerging Therapeutic Indicators in Lung AdenocarcinomaSemantic proximity Read ↗

Landscape of Immune Microenvironment Under Immune Cell Infiltration Pattern in Breast Cancer.Semantic proximity Read ↗

The Immune Landscape of CancerSemantic proximity Read ↗

A specific immune signature for predicting the prognosis of glioma patients with IDH1-mutation and guiding immune checkpoint blockade therapy.Semantic proximity Read ↗

Identification of Prostate Cancer Subtypes Based on Immune Signature Scores in Bulk and Single Cell TranscriptomesSemantic proximity Read ↗

Pan-cancer tumor classification by a holistic tumor microenvironment atlasSemantic proximity Read ↗

An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvironment.Semantic proximity Read ↗

Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.