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Article

The impact of radiation on glioblastoma evolution

2020-01-01

Abstract excerpt

Glioblastoma (GB) is the most common and malignant primary adult brain cancer with a median survival of 15 months despite treatment with surgical resection followed by chemo-radiotherapy. The clonal diversity and evolutionary dynamics inherent to GBs is considered a major obstacle to effective treatment response. While studies have focused on temozolomide, a role for radiotherapy as an independent driver of GB evo...

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Literature Corpus work
ea3e8426-713a-5dd0-ba69-9a6acdb5fdd6
DOI
10.17863/cam.49064
Open publication

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The impact of radiation on glioblastoma evolutionDOI 10.17863/cam.49064
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