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Targeting Radiation-Induced Glioma-Initiating Cells in Patient-Derived Glioblastoma

2025-10-09

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Glioblastoma (GB) is a highly aggressive and treatment-resistant brain cancer with poor prognosis. Surgical resection followed by radiotherapy (RT) with the chemotherapeutic, temozolomide (TMZ), is the standard GB treatment; yet recurrence often occurs. GB is organized hierarchically with a small population of radiation-resistant glioma-initiating cells (GICs) that self-rene...

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Literature Corpus work
1c09104e-5a2d-5fad-aaeb-3207635af834
DOI
10.1101/2025.10.08.681196
Open publication

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Targeting Radiation-Induced Glioma-Initiating Cells in Patient-Derived GlioblastomaDOI 10.1101/2025.10.08.681196
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