Article

Impact of the radiated brain microenvironment on a panel of human patient-derived xenografts

2020-06-04

Abstract excerpt

<h4>Objective</h4> Radiotherapy, combined with surgical resection and chemotherapy, remains a first-line treatment for infiltrative gliomas. However, these tumor are not surgically curable, and often recur, even within the prior radiation field, and may demonstrate a more aggressive phenotype. We recently demonstrated that the radiated brain tumor microenvironment promotes tumor aggressiveness in an orthotopic pa...

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Identifiers and source

Literature Corpus work: 8fa46381-2391-59d2-a010-a7218aa27439
DOI: 10.1101/2020.06.03.132365

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