Article

Structures of Coxsackievirus A10 unveil the molecular mechanisms of receptor binding and viral uncoating

2018-11-20

Abstract excerpt

Abstract Coxsackievirus A10 (CVA10), a human type-A Enterovirus (HEV-A), can cause diseases ranging from hand-foot-and-mouth disease to polio-myelitis-like disease. CVA10, together with some other HEV-As, utilizing the molecule KREMEN1 as an entry receptor, constitutes a KREMEN1-dependent subgroup within HEV-As. Currently, there is no vaccine or antiviral therapy available for treating diseases caused by CVA10. Th...

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Literature Corpus work: e9dc68ca-0e21-5879-b069-33bc6f0acdaf
DOI: 10.1038/s41467-018-07531-0

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