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Structural Analysis of Coxsackievirus A7 Reveals Conformational Changes Associated with Uncoating

19 Apr 2012

Abstract excerpt

Coxsackievirus A7 (CAV7) is a rarely detected and poorly characterized serotype of the Enterovirus species Human enterovirus A (HEV-A) within the Picornaviridae family. The CAV7-USSR strain has caused polio-like epidemics and was originally thought to represent the fourth poliovirus type, but later evidence linked this strain to the CAV7-Parker prototype. Another isolate, CAV7-275/58, was also serologically...

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PMID: 22514349
DOI: 10.1128/jvi.06425-11

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