Article

Erosion of regenerative regulation: age-associated shifts in the skeletal muscle fiber epigenome and transcriptome

2026-08-24

Abstract excerpt

Skeletal muscle aging is characterized by the deterioration of muscle function, which can lead to negative quality-of-life outcomes including frailty and sarcopenia. While understanding the mechanisms of this process is increasingly important as the global population ages, previous molecular studies of skeletal muscle aging have been limited by statistical power and cell type resolution. In this study, we analyzed...

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Literature Corpus work: 8a2e9592-1b32-5ccc-a25d-e5360e35fce6
DOI: 10.64898/2026.08.19.744884

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