Article
Deubiquitinating Enzyme Amino Acid Profiling Reveals a Class of Ubiquitin Esterases
2020-05-12
Abstract excerpt
The reversibility of ubiquitination by the action of deubiquitinating enzymes (DUBs) serves as an important regulatory layer within the ubiquitin system. Approximately 100 DUBs are encoded by the human genome and many have been implicated with pathologies including neurodegeneration and cancer. Non-lysine ubiquitination is chemically distinct and its physiological importance is emerging. Here we couple chemically...
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Identifiers and source
- Literature Corpus work
- e9402080-821e-56ce-b599-33929bc263ec
- DOI
- 10.1101/2020.05.11.087965