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Deubiquitinating enzymes as cancer biomarkers: new therapeutic opportunities?

31 Mar 2019

Abstract excerpt

Cancer remains a life-threatening disease and accounts for the major mortality rates worldwide. The practice of using biomarkers for early detection, staging, and customized therapy may increase cancer patients' survival. Deubiquitinating enzymes (DUBs) are a family of proteases that remove ubiquitin tags from proteins of interest undergoing proteasomal degradation. DUBs play several functional roles other than...

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Histone Deacetylase Inhibitors Research
Peptidase Inhibition and Analysis
Ubiquitin and proteasome pathways

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30760385
DOI: 10.5483/bmbrep.2019.52.3.048

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