Article

M <sup>6</sup> A reduction relieves FUS-associated ALS granules

2023-10-26

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease due to gradual motorneurons (MN) degeneration 1 . Among the processes associated to ALS pathogenesis, there is the formation of cytoplasmic inclusions produced by mutant protein aggregation, among which the RNA binding protein FUS 2 . In this work we show that such inclusions are significantly reduced in number and dissolve faster wh...

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Literature Corpus work: e8f774d7-77cb-5d5a-92fb-e29870023f2d
DOI: 10.1101/2023.10.25.563954

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