Article

HBV Genome-Enriched Single Cell Sequencing Revealed Heterogeneity in HBV-Driven HCC

2021-05-19

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>HBV-HCC is heterogeneous and frequently contains multifocal tumors. To interrogate heterogeneity of HBV-HCC, we developed a HBV genome enriched single cell sequencing (HGE-scSeq) procedure and a computational method to identify HBV integration sites and infer DNA copy number variations (CNVs). <bold>Results:</bold> We performed HGE-scSeq on 269 cells from 4 tumo...

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Literature Corpus work: e8ec6993-9a0a-5ae2-a645-208de361f1ff
DOI: 10.21203/rs.3.rs-537064/v1

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