Article
Disparity landscapes of viral-induced structural variations in HCC: Mechanistic characterization and functional implications
13 Sept 2024
Abstract excerpt
BACKGROUND AND AIMS: HCC is the most common type of primary liver cancer and is a common malignancy worldwide. About half of all new liver cancers worldwide each year occur in China, including Hong Kong, due to a high prevalence of HBV infection. HBV DNA integrates into the human genome, disrupting the endogenous tumor suppressors/regulatory genes or enhancing the activity of proto-oncogenes. It would be useful...
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