Article

Puberty Blocker and Aging Impact on Testicular Cell States and Function

2024-03-27

Abstract excerpt

Spermatogonial stem cell (SSC) acquisition of meiotogenetic state during puberty to produce genetically diverse gametes is blocked by drugs collectively referred as ‘puberty blocker’ (PB). Investigating the impact of PB on juvenile SSC state and function is challenging due to limited tissue access and clinical data. Herein, we report largest clinically annotated juvenile testicular biorepository with all children...

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Literature Corpus work: e8ddea86-02cf-58a4-9b44-f3f3772699f5
DOI: 10.1101/2024.03.23.586441

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