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The Dynamic Transcriptional Cell Atlas of Testis Development during Human Puberty

9 Jan 2020

Abstract excerpt

The human testis undergoes dramatic developmental and structural changes during puberty, including proliferation and maturation of somatic niche cells, and the onset of spermatogenesis. To characterize this understudied process, we profiled and analyzed single-cell transcriptomes of ∼10,000 testicular cells from four boys spanning puberty and compared them to those of infants and adults. During puberty,...

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PMID: 31928944
DOI: 10.1016/j.stem.2019.12.005

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