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Applying Single-Cell Analysis to Gonadogenesis and DSDs (Disorders/Differences of Sex Development)

10 Sept 2020

Abstract excerpt

The gonads are unique among the body's organs in having a developmental choice: testis or ovary formation. Gonadal sex differentiation involves common progenitor cells that form either Sertoli and Leydig cells in the testis or granulosa and thecal cells in the ovary. Single-cell analysis is now shedding new light on how these cell lineages are specified and how they interact with the germline. Such studies are...

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PMID: 32927658
DOI: 10.3390/ijms21186614

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