Article

Dynamic transcriptome profiles within spermatogonial and spermatocyte populations during postnatal testis maturation revealed by single-cell sequencing

2018-11-06

Abstract excerpt

Spermatogenesis is the process by which male gametes are formed from a self-renewing population of spermatogonial stem cells (SSCs) residing in the testis. SSCs represent less than 1% of the total testicular cell population, but must achieve a stable balance between self-renewal and differentiation. Once differentiation has occurred, the newly formed and highly proliferative spermatogonia must then enter the meiot...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8d37ae6a-96b0-510d-aa1d-a457c1c17012
DOI: 10.1101/464149

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Dynamic transcriptome profiles within spermatogonial and spermatocyte populations during postnatal testis maturation revealed by single-cell sequencingDOI 10.1101/464149Read

The Mammalian Spermatogenesis Single-Cell Transcriptome, from Spermatogonial Stem Cells to SpermatidsSemantic proximity Read

Single-cell RNA sequencing of human, macaque, and mouse testes uncovers conserved and divergent features of mammalian spermatogenesisSemantic proximity Read

What has single-cell RNA-seq taught us about mammalian spermatogenesis?Semantic proximity Read

A dynamic transcriptional cell atlas of testes development after birth in Hu sheepSemantic proximity Read

Mapping the Development of Human Spermatogenesis Using Transcriptomics-Based Data: A Scoping ReviewSemantic proximity Read

Decoding the Spermatogenesis Program: New Insights from Transcriptomic AnalysesSemantic proximity Read

Staged developmental mapping and X chromosome transcriptional dynamics during mouse spermatogenesisSemantic proximity Read

A single-cell multiomics roadmap of zebrafish spermatogenesis reveals regulatory principles of male germline formationSemantic proximity Read

Adult Human, but Not Rodent, Spermatogonial Stem Cells Retain States with a Foetal-like SignatureSemantic proximity Read

Unraveling transcriptome dynamics in human spermatogenesisSemantic proximity Read

The adult human testis transcriptional cell atlasSemantic proximity Read

Understanding testicular single cell transcriptional atlas: from developmental complications to male infertilitySemantic proximity Read