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Genome-wide Perturbation Analysis Screening System for Exosomes-Related Genes Based on the CRISPR/Cas9 Platform

2023-09-08

Abstract excerpt

As reported previously, exosomes have significant impacts on the physiological and pathological state in vivo . Exosomes have been extensively studied as a drug delivery carrier and some exosomes drugs have been undergoing clinical research. The mechanisms of exosome production, transport, and secretion remain to be studied in depth. Thus, here, we developed a novel CRISPR-UMI-based gene screening system, with wh...

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Literature Corpus work
e8cdbad1-3837-5751-9381-b70fac76d22b
DOI
10.1101/2023.09.07.556640
Open publication

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Genome-wide Perturbation Analysis Screening System for Exosomes-Related Genes Based on the CRISPR/Cas9 PlatformDOI 10.1101/2023.09.07.556640
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