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Exosome theranostics: Comparative analysis of P body and exosome proteins and their mutations for clinical applications.

Functional & integrative genomics - 12 Jul 2024

Satheeshan Greeshma, Si Ayan Kumar, Rutta Joel, Venkatesh Thejaswini

Abstract excerpt

Exosomes are lipid-bilayered vesicles, originating from early endosomes that capture cellular proteins and genetic materials to form multi-vesicular bodies. These exosomes are secreted into extracellular fluids such as cerebrospinal fluid, blood, urine, and cell culture supernatants. They play a key role in intercellular communication by carrying active molecules like lipids, cytokines, growth factors,...

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PMID: 38995459
DOI: 10.1007/s10142-024-01404-0

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