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Article

Gene Editing by Extracellular Vesicles.

International journal of molecular sciences - 5 Oct 2020

Kostyushev Dmitry, Kostyusheva Anastasiya, Brezgin Sergey, Smirnov Valery, Volchkova Elena, Lukashev Alexander, Chulanov Vladimir

Abstract excerpt

CRISPR/Cas technologies have advanced dramatically in recent years. Many different systems with new properties have been characterized and a plethora of hybrid CRISPR/Cas systems able to modify the epigenome, regulate transcription, and correct mutations in DNA and RNA have been devised. However, practical application of CRISPR/Cas systems is severely limited by the lack of effective delivery tools. In this...

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Identifiers

PMID: 33028045
DOI: 10.3390/ijms21197362
PMCID: PMC7582630

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