Article

Application of spatial transcriptomics across organoids: a high-resolution spatial whole-transcriptome benchmarking dataset

2025-05-09

Abstract excerpt

<h4>Summary</h4> Stem cell-derived organoids hold promise to model tissue-specific disease. To enable this, it is crucial to assess how transcriptional signatures, cellular organisation and composition of organoids compare to in vivo counterparts. However, technologies which elucidate regional molecular identity, like spatial transcriptomics, have been challenging to apply to organoids. This study presents the f...

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Literature Corpus work: c5a3fe46-a210-5a27-9ff2-cdd683f79ab8
DOI: 10.1101/2025.05.04.651803

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