Article

Activation of Smad 2/3 signaling by low shear stress mediates artery inward remodeling

2019-07-05

Abstract excerpt

<h4>Rationale</h4> Blood vessel remodeling in response to changes in tissue demand is an important aspect of fitness and is often compromised in vascular disease. Endothelial cell (EC) sensing of fluid shear stress (FSS) governs vessel remodeling to maintain FSS at a specific magnitude or set point in healthy vessels. <h4>Objective</h4> The purpose of this study was to understand how shear stress-regulated Smad...

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Literature Corpus work: e8b0c104-9b01-5c0c-bdd6-801fbaecb61e
DOI: 10.1101/691980

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