Article

Evolution of the proinflammatory receptor TREM-1 in mammals reveals signatures of pathogen-driven conflict

2026-08-09

Abstract excerpt

<h4>ABSTRACT</h4> Animal immune cells express a range of surface receptors that promote the detection of diverse host and pathogen-derived molecules. The triggering receptors expressed on myeloid cells (TREMs) encompass a family of cell surface receptors involved in the modulation of immune signaling cascades. Mammalian TREM-1 has emerged as a critical mediator of antibacterial immune defense and inflammatory dis...

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Literature Corpus work: e8a7ca99-270f-5715-acbe-1c9fc779d906
DOI: 10.64898/2026.08.05.743136

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