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Article

Evolutionary insights into host-pathogen interactions from mammalian sequence data.

Nature reviews. Genetics - 1 Apr 2015

Sironi Manuela, Cagliani Rachele, Forni Diego, Clerici Mario

Abstract excerpt

Infections are one of the major selective pressures acting on humans, and host-pathogen interactions contribute to shaping the genetic diversity of both organisms. Evolutionary genomic studies take advantage of experiments that natural selection has been performing over millennia. In particular, inter-species comparative genomic analyses can highlight the genetic determinants of infection susceptibility or...

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Identifiers

PMID: 25783448
DOI: 10.1038/nrg3905
PMCID: PMC7096838

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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