Article

Neuroendocrinology of the lung revealed by single cell RNA sequencing

2022-03-10

Abstract excerpt

<h4>ABSTRACT</h4> Pulmonary neuroendocrine cells (PNECs) are sensory epithelial cells that transmit airway status to the brain via sensory neurons and locally via CGRP and GABA. Several other neuropeptides and neurotransmitters have been detected in various species, but the number, targets, functions, and conservation of PNEC signals are largely unknown. We used scRNAseq to profile hundreds of the rare mouse and...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e86efc63-993e-5a61-a382-350ce9af319f
DOI: 10.1101/2022.03.08.483399

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Neuroendocrinology of the lung revealed by single cell RNA sequencingDOI 10.1101/2022.03.08.483399Read

Pulmonary neuroendocrine cells: physiology, tissue homeostasis and diseaseSemantic proximity Read

A robust human airway organoid platform enables scalable expansion and trajectory mapping of pulmonary neuroendocrine cellsSemantic proximity Read

Developmental origins of cell heterogeneity in the human lungSemantic proximity Read

A topographic atlas defines developmental origins of cell heterogeneity in the human embryonic lungSemantic proximity Read

A single-cell transcriptomic comparison between small intestinal neuroendocrine tumors and their progenitorSemantic proximity Read

A single-cell atlas of the human healthy airwaysSemantic proximity Read

Pulmonary neuroendocrine cells function as airway sensors to control lung immune response.Semantic proximity Read

A spatial multi-omics atlas of the human lung reveals a novel immune cell survival nicheSemantic proximity Read

The Human and Mouse Enteric Nervous System at Single-Cell Resolution.Semantic proximity Read

Single-nuclei transcriptomes from human adrenal gland reveal distinct cellular identities of low and high-risk neuroblastoma tumorsSemantic proximity Read

Single-nuclei transcriptomes from human adrenal gland reveals distinct cellular identities of low and high-risk neuroblastoma tumorsSemantic proximity Read

Dissecting the cellular specificity of smoking effects and reconstructing lineages in the human airway epitheliumSemantic proximity Read