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Pulmonary neuroendocrine cells: physiology, tissue homeostasis and disease

1 Dec 2020

Abstract excerpt

Mammalian lungs have the ability to recognize external environments by sensing different compounds in inhaled air. Pulmonary neuroendocrine cells (PNECs) are rare, multi-functional epithelial cells currently garnering attention as intrapulmonary sensors; PNECs can detect hypoxic conditions through chemoreception. Because PNEC overactivation has been reported in patients suffering from respiratory diseases - such...

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PMID: 33355253
DOI: 10.1242/dmm.046920

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