Article

Developmental origins of cell heterogeneity in the human lung

2022-01-12

Abstract excerpt

<h4>Summary</h4> The lung contains numerous specialized cell-types with distinct roles in tissue function and integrity. To clarify the origins and mechanisms generating cell heterogeneity, we created a first comprehensive topographic atlas of early human lung development. We report 83 cell states, several spatially-resolved developmental trajectories and predict cell interactions within defined tissue niches. We...

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Literature Corpus work: debe8330-ad78-52c0-958c-c4d466df1805
DOI: 10.1101/2022.01.11.475631

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