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Article

Small circRNAs with self-cleaving ribozymes are frequently expressed in metazoan transcriptomes

2019-08-01

Abstract excerpt

Ribozymes are catalytic RNAs present in modern genomes but considered as remnants of a prebiotic RNA world. The paradigmatic hammerhead ribozyme (HHR) is a small self-cleaving motif widespread from bacterial to human genomes. Here, we report that most of the classical type I HHRs frequently found in the genomes of diverse animals are contained within a novel family of non-autonomous non-LTR retrotransposons. These...

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Literature Corpus work
e869a1db-0852-55e3-a59f-cb64aaf282ba
DOI
10.1101/721605
Open publication

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Small circRNAs with self-cleaving ribozymes are frequently expressed in metazoan transcriptomesDOI 10.1101/721605
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