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Circular RNAs Are Regulators of Diverse Animal Transcriptomes: One Health Perspective

18 Sept 2020

Abstract excerpt

Derived from linear (parental) precursor mRNA, circRNA are recycled exons and introns whose ends are ligated. By titrating microRNAs and RNA binding proteins, circRNA interconnect networks of competing endogenous RNAs. Without altering chromosomal DNA, circRNA regulates skeletal muscle development and proliferation, lactation, ovulation, brain development, and responses to infections and metabolic stress. This...

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PMID: 33193584
DOI: 10.3389/fgene.2020.00999

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