Article

Tunable DNA Origami Nanosensors for Detection of Multiscale Spatial Ion Concentration Gradients

2025-10-16

Abstract excerpt

Ion gradients play a vital role in cellular signaling, mechanobiology, and organ-level homeostasis. Despite their importance, accurately mapping these spatial gradients at biologically relevant length scales remains a challenge due to the limited tunability and spatial resolution of conventional fluorescent sensors. Here, we present a DNA origami-based sensor (NanoDyn) with tunable sensitivity that enables the det...

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Literature Corpus work: e868d88d-fea4-5eae-b313-49b758f80e32
DOI: 10.1101/2025.10.16.682652

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