Article

Modular DNA-origami-based nanoarrays enhanced cell binding-affinity through “lock-key” interaction

2022-10-18

Abstract excerpt

<title>Abstract</title> <p>Surface proteins of cells are generally recognized through receptor-ligand interactions (RLIs) in disease diagnosis, but their nonuniform spatial distribution and high-order structure lead to low binding-affinity. Constructing nano-topologies that match the spatial distribution of membrane proteins to improve binding-affinity remains a challenge. Inspired by the multi-antigen recognitio...

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Literature Corpus work: 87a4373e-93e9-5386-ad6c-3fbe942cc1eb
DOI: 10.21203/rs.3.rs-2148903/v1

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