Article

Visualizing and Quantifying microRNA Induced DNA Origami Separation at the Nanoscale

2025-08-19

Abstract excerpt

Circulating microRNAs (miRNAs) are promising biomarkers for disease diagnosis, but their small size and instability hinder direct detection. The detection of small RNA, such as miRNA, using solid-state nanopores typically involves the binding of miRNA to a larger carrier molecule to generate detectable signals. However, this approach is prone to RNAse degradation in the environment leading to accidental digestion...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: dd824498-f64a-5869-baeb-91c6a079d9ee
DOI: 10.1101/2025.08.15.670511

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Visualizing and Quantifying microRNA Induced DNA Origami Separation at the NanoscaleDOI 10.1101/2025.08.15.670511Read

DNA nanotechnology assisted nanopore-based analysisSemantic proximity Read

Single-molecule analysis using DNA origami.Semantic proximity Read

Fluorinated RNA origami enables serum-stable nanodevices for sensing and targetingSemantic proximity Read

Stacking effects on mutation detection by T4 DNA ligation within dimeric DNA origami triangle barcodes for single-molecule nanopore analysisSemantic proximity Read

Target Recycling Amplification Process for Digital Detection of Exosomal MicroRNAs Through Photonic Resonator Absorption MicroscopySemantic proximity Read

MEMO: A Micro Memo Sensor Detecting microRNA-RISC using an Accurate Cell-Free Expression PlatformSemantic proximity Read

Single-cell precision nanotechnology <i>in vivo</i>Semantic proximity Read

<i>In Situ</i> Unzipping of Long, High Molecular Weight DNA in Solid State NanoporesSemantic proximity Read

Addressing the instability of DNA nanostructures in tissue culture.Semantic proximity Read

Integrating DNA-strand-displacement circuitry with self-assembly of spherical nucleic acids.Semantic proximity Read

Multiarmed DNA jumper and Metal-Organic Frameworks–Functionalized Paper-based Bioplatform for Small Extracellular Vesicle–derived miRNAs AssaySemantic proximity Read

Rapid Kinetic Fingerprinting of Single Nucleic Acid Molecules by a FRET-based Dynamic NanosensorSemantic proximity Read