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CYP3A5 genotyping-guided dosing versus weight-based dosing in a multi-ethnic population of kidney transplant recipients

2025-07-01

Abstract excerpt

Introduction Tacrolimus is the cornerstone of immunosuppression after kidney transplantation (KTx) and is characterized by a narrow therapeutic index and large inter-individual variability. Pre-transplant CYP3A5 genotyping to guide tacrolimus dosing may help achieve target levels more rapidly and improve outcomes, but its impact remains unclear in our local multiethnic population where CYP3A5 expression may differ...

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Literature Corpus work
e8669001-84aa-51ec-a6bb-24ec4fdccfd6
DOI
10.1177/20101058251365300
Open publication

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CYP3A5 genotyping-guided dosing versus weight-based dosing in a multi-ethnic population of kidney transplant recipientsDOI 10.1177/20101058251365300
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