Article
Clinical Impact of the Adaptation of Initial Tacrolimus Dosing to the CYP3A5 Genotype After Kidney Transplantation: Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Clinical pharmacokinetics - 1 Jul 2021
Yang Hui, Sun Yiqi, Yu Xiaojia, Hu Xiaopeng, Wang Wei, Zhang Xiaodong, Liu Lihong
Abstract excerpt
OBJECTIVE: The aim of this systematic review and meta-analysis was to compare the clinical outcomes between genotype-guided and conventional tacrolimus doses in kidney transplantation patients. MATERIALS AND METHODS: We performed a comprehensive literature search of the PubMed, EMBASE, and Cochrane databases from the date of inception to 26 February 2020. References of the retrieved articles were also reviewed...
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