Article

Anti-HBsAg antibody mAb19-LS enhances antiviral immunity in humans with chronic hepatitis B

2026-07-06

Abstract excerpt

Chronic infection with hepatitis B virus (HBV) is characterized by persistent expression of hepatitis B surface antigen (HBsAg), which is associated with profound immune tolerance. Although nucleos(t)ide analogue therapy effectively suppresses viral replication, it neither eliminates HBV nor reverses virus-specific immune dysfunction. Here, we report the results of two parallel first-in-human, dose-escalation stud...

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Literature Corpus work: e8477114-75b5-5f52-adee-ccfeff3f691b
DOI: 10.64898/2026.07.03.26357226

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