Article

Endothelial Resolution of Inflammation is Delayed Following JAK-driven but not NFκB-dependent Activation

2021-06-18

Abstract excerpt

Blood endothelial cells actively regulate egress of leukocytes into peripheral tissues in response to inflammatory insult. The resolution of inflammation is critical for healing and return to homeostasis, but the timing and mechanisms involved in return to a non-inflamed state are not well-understood. We examined vascular endothelial activation comparing NFκB-driven TNFα and JAK/STAT-mediated IFNγ. Pro-adhesive ge...

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Literature Corpus work: e8409122-3a51-5228-94d5-3b60e2115a43
DOI: 10.1101/2021.06.18.449043

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