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Article

Genetic polymorphisms in the P2X7 gene and its association with susceptibility to tuberculosis.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Feb 2012

Singla N, Gupta D, Joshi A, Batra N, Singh J

Abstract excerpt

BACKGROUND: Several studies have reported the influence of genetic variations on susceptibility to tuberculosis (TB). Polymorphism in P2X7 gene coding for P2X7 receptor present on macrophages has been linked to TB in different populations. OBJECTIVE: To assess the role of P2X7 gene -762T/C and -1513A/C polymorphisms in TB susceptibility. DESIGN: In a case-control study, polymerase chain reaction (PCR)...

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Identifiers

PMID: 22137490
DOI: 10.5588/ijtld.11.0076

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