Article
Single Nucleotide Polymorphisms in P2X7 Gene Are Associated with Serum Immunoglobulin G Responses to Mycobacterium tuberculosis in Tuberculosis Patients.
Disease markers - 1 Jan 2015
Wu Jiangdong, Lu Lijun, Zhang Le, Ding Yulei, Wu Fang, Zuo Weize, Zhang Wanjiang
Abstract excerpt
OBJECTIVE: Our study investigated the association between single nucleotide polymorphisms (SNPs) in P2X7 gene and serum immunoglobulin G (IgG) responses to mycobacterium tuberculosis (MTB) in TB patients. METHODS: A total of 103 TB patients were enrolled as case group and 87 healthy individuals at same geographical region as control group. The SNP detection of 1513A>C and -762T>C was performed using PCR-RFLP, and...
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