Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of P2X7 receptor +1513 (A-->C) polymorphism with tuberculosis in a Punjabi population.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Sept 2010

Sharma S, Kumar V, Khosla R, Kajal N, Sarin B, Sehajpal P

Abstract excerpt

BACKGROUND: Development of tuberculosis (TB) disease is an outcome of complex host-pathogen interactions. The purinergic P2X(7) receptors are adenosine triphosphate gated molecules shown to induce killing of intracellular Mycobacterium tuberculosis, followed by apoptosis of the infected macrophage. A single nucleotide polymorphism in exon 13 of the P2X(7) receptors gene at +1513 position has been shown to abolish...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mycobacterium tuberculosis

Share to Receptors, Purinergic P2X7

Share to Risk Factors

Share to Tuberculosis

Share to Young Adult

Source

Identifiers

PMID: 20819262

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of P2X7 receptor +1513 (A-->C) polymorphism with tuberculosis in a Punjabi population.PMID 20819262Read ↗

P2X7 receptor polymorphisms and susceptibility to tuberculosis in a North Indian Punjabi population.Semantic proximity Read ↗

The effect of P2X7 receptor 1513 polymorphism on susceptibility to tuberculosis: A meta-analysis.Semantic proximity Read ↗

P2X7 Gene Polymorphisms and Risk Assessment for Pulmonary Tuberculosis in Asian IndiansSemantic proximity Read ↗

P2X7 gene polymorphisms and risk assessment for pulmonary tuberculosis in Asian Indians.Semantic proximity Read ↗

Contribution of the P2X7 1513A/C loss-of-function polymorphism to extrapulmonary tuberculosis susceptibility in Tunisian populations.Semantic proximity Read ↗

Association of P2X7 gene polymorphisms with susceptibility to pulmonary tuberculosis in Zahedan, Southeast Iran.Semantic proximity Read ↗

Association of P2X7 A1513C (rs3751143) gene polymorphism with risk of tuberculosis: evidence from a meta-analysis.Semantic proximity Read ↗

A polymorphism in the P2X7 gene increases susceptibility to extrapulmonary tuberculosis.Semantic proximity Read ↗

A meta-analysis of P2X7 gene-1513A/C polymorphism and pulmonary tuberculosis susceptibility.Semantic proximity Read ↗

Lack of association of 1513 A/C polymorphism in P2X7 gene with susceptibility to pulmonary and extrapulmonary tuberculosis.Semantic proximity Read ↗

Genetic polymorphisms in the P2X7 gene and its association with susceptibility to tuberculosis.Semantic proximity Read ↗

Mycobacterium tuberculosis co-existence with humans: making an imprint on the macrophage P2X(7) receptor gene?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.