Article
Association of P2X7 receptor +1513 (A-->C) polymorphism with tuberculosis in a Punjabi population.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Sept 2010
Sharma S, Kumar V, Khosla R, Kajal N, Sarin B, Sehajpal P
Abstract excerpt
BACKGROUND: Development of tuberculosis (TB) disease is an outcome of complex host-pathogen interactions. The purinergic P2X(7) receptors are adenosine triphosphate gated molecules shown to induce killing of intracellular Mycobacterium tuberculosis, followed by apoptosis of the infected macrophag...
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