Article
P2X7 receptor polymorphisms and susceptibility to tuberculosis in a North Indian Punjabi population.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Aug 2018
Chaudhary A, Singh J P, Sehajpal P K, Sarin B C
Abstract excerpt
BACKGROUND: Genetic elements are known to influence susceptibility to tuberculosis (TB). P2X7R is a candidate gene with multiple single-nucleotide polymorphisms (SNPs) that has the potential to influence an individual's ability to kill the intracellular pathogen Mycobacterium tuberculosis. OBJECTIVE: To explore the role of five functional polymorphisms of P2X7R in susceptibility or resistance to TB in a North...
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