Article
Association of P2X7 gene polymorphisms with susceptibility to pulmonary tuberculosis in Zahedan, Southeast Iran.
Genetics and molecular research : GMR - 24 Jan 2013
Bahari G, Hashemi M, Taheri M, Naderi M, Moazeni-Roodi A, Kouhpayeh H R, Eskandari-Nasab E
Abstract excerpt
Susceptibility to tuberculosis may be influenced by variations in human genes. The P2X7 receptor is an ATP-gated cation channel expressed in immune cells, and it influences the release of proinflammatory cytokines from monocytes and macrophages. In the present study, we aimed to evaluate the impact of P2X7 gene rs2393799 (-762T/C) and rs1718119 (Thr348Ala) polymorphisms on patient susceptibility to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
