Article

GPR17 modulates oligodendrocyte precursor cell maturation during development but has limited impact on myelin regeneration following demyelinating insults

2025-07-11

Abstract excerpt

Pharmacological enhancement of myelin regeneration is broadly recognized as the next frontier in therapeutic approaches for demyelinating diseases of the CNS such as multiple sclerosis. However, although several molecular targets for remyelination have been tested preclinically and in clinical trials, an efficacious and safe myelin repair treatment is yet to be developed. One promising molecular target to enhance...

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Literature Corpus work: e7d14a9e-b1f4-5eb1-a43a-32a0a6edaa09
DOI: 10.1101/2025.07.08.659146

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