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Article

Analysis of the GPR17 receptor in NG2 ‐glia under physiological conditions unravels a new subset of oligodendrocyte progenitor cells with distinct functions

23 Feb 2023

Abstract excerpt

Abstract NG2‐glia comprise a heterogeneous population of cycling cells that give rise to mature, myelinating oligodendrocytes. The mechanisms that regulate the process of differentiation from NG2‐glia into oligodendrocytes are still not fully understood but over the last years the G Protein‐coupled Receptor 17 (GPR17) has been on the spotlight as a possible key regulator. Interestingly, GPR17‐expressing NG2‐glia...

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PMID: 36815579
DOI: 10.1002/glia.24356

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