Article

Enterovirus-driven interferon signaling induces epithelial TG2 via JAK-STAT: Implications for the onset of celiac disease

2026-05-29

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background & Aims</h4> Celiac disease (CeD) is an autoimmune disorder triggered by dietary gluten in genetically predisposed individuals, but environmental factors contributing to disease onset remain incompletely defined. Epidemiological studies implicate enterovirus infections as potential triggers. Here, we investigated the epithelial-intrinsic mechanisms by which coxsackievirus B1 (CVB1...

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Literature Corpus work: e786f84d-013f-5112-9a0d-9870d8ed1591
DOI: 10.64898/2026.05.26.727875

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