Article

Quantitative Assessment of shRNA Loading and Delivery Efficiency of Engineered Extracellular Vesicles

2026-06-09

Abstract excerpt

RNA interference (RNAi) therapeutics enable selective silencing of disease-associated genes. Yet, their clinical application remains largely confined to the liver due to extrahepatic delivery constraints of current platforms such as GalNAc conjugates and lipid nanoparticles. Extracellular vesicles (EVs) offer an attractive alternative delivery strategy owing to their biocompatibility, ability to traverse biologica...

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Literature Corpus work: e751c246-ce37-5d84-94a3-b723d5ce85bf
DOI: 10.64898/2026.06.05.730346

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