Article

Rapid establishment of a tumor-retained state curtails the contribution of conventional NK cells to anti-tumor immunity in solid cancers

2023-08-14

Abstract excerpt

Immune cell dysfunction within the tumor microenvironment undermines the control of cancer progression. NK cells play critical roles in limiting early tumor growth and metastatic disease, however, established cancers contain a phenotypically distinct, tumor-specific NK cell compartment. The temporal dynamics, mechanistic underpinning and functional significance of this tumor NK pool remains incompletely understood...

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Literature Corpus work: e749d006-5e71-5867-9b1f-bf19caa3a6f6
DOI: 10.1101/2023.08.10.552797

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