Article

Single-cell transcriptomics reveals that tumor-infiltrating natural killer cells are activated by localized ablative immunotherapy and share anti-tumor signatures induced by immune checkpoint inhibitors

2023-05-03

Abstract excerpt

<h4>Rationale</h4> Natural killer (NK) cells provide protective anti-cancer immunity. However, the cancer therapy induced activation gene signatures and pathways in NK cells remain unclear. <h4>Methods</h4> We applied a novel localized ablative immunotherapy (LAIT) by synergizing photothermal therapy (PTT) with intra-tumor delivering of the immunostimulant N-dihydrogalactochitosan (GC), to treat breast cancer us...

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Literature Corpus work: 4689d203-f986-5543-9701-b807b9d69693
DOI: 10.1101/2023.05.02.539163

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Single-cell transcriptomics reveals that tumor-infiltrating natural killer cells are activated by localized ablative immunotherapy and share anti-tumor signatures induced by immune checkpoint inhibitorsDOI 10.1101/2023.05.02.539163Read

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