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Re-Evaluating Cancer Stem Cells (CSCs) and Polyploid Giant Cancer Cells (PGCCs) in the Light of Evolutionary Cancer Cell Biology ECCB

2024-09-02

Abstract excerpt

According to evolutionary cancer cell biology ECCB, cancer stem cells do not arise from normal stem cells, but rather from the functional ACD phenotype of the germline. This phenotype proliferates through asymmetric cell division, producing self-renewing cells and non-proliferating daughter cells with cancer stem cell qualities (CSCs). ECCB posits that cancer stem cells themselves do not proliferate. Similar to pr...

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Literature Corpus work: e6b99a24-a861-5d15-8e46-3fea8749729f
DOI: 10.20944/preprints202409.0026.v1

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